Theresa
Verified Customer
Interesting cream, I was a bit skeptical. But it has proven to be very effective. Light weight, seeps into the skin nicely. There is no residue that some creams often give off. I will purchase again once this one is complete. I like the fact that it comes in the case and for torture purchases only the refill needs to be replaced. Excellent!!

OS-01 FACE Topical Supplement

OS-01 FACE Topical Supplement

  15K+ Bought in past month
$115.95
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Smooth and firm skin with our daily moisturizer for the face and neck, powered by the OS-01 Peptide™.01

  • Boosts hydration, elasticity, and barrier function
  • 96% showed an improvement in firmness and radiance
  • Dermatologist tested, fragrance-free, safe for sensitive skin
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HeaClean + Safe Ingredients

Our products are non-comedogenic (non-pore clogging), 100% free from fragrance.parabens, sulfates, lanolin, MCl/Ml, DEA, heavy metals, talc, petrolatum/paraffin/mineraloil, gluten, phthalates, PFAs and do not contain unnecessary emulsifiers, preservatives.and solvents.

Benefits

Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment

Hydration

Boosts barrier function, allowing your skin to retain moisture and stay hydrated.02

Firmness

Switches off the cells that degrade collagen, helping skin stay firm.01,03

Radiance

Enhances skin tone and texture, helping skin look and feel smooth and radiant.02

5-STAR REVIEWS

See why customers love OS-01 FACE

“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

The proof is in the pictures

    Visible results, scientifically validated

    CLINICAL DATA

    100%

    of participants had improved smoothness 02

    96%

    of participants had improved firmness, radiance, and tone 02

    90%

    of participants had improved elasticity 02

    86%

    of participants had improved appearance of fine lines and wrinkles 02

    Caption about the results and/or link for their proof.

    The Science Behind OS-01 FACE

    With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:

    1. Increases epidermal thickness 01
    2. Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) 01,03
    3. Promotes cellular proliferation (increase in MKI67) 01

    Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE

    6 active ingredients that complement the OS-01 peptide

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    Pracaxi Oil

    Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.

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    Niacinamide

    A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.

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    Allantoin

    A skin-conditioning molecule that moisturizes and soothes irritated skin.

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    Andiroba Oil

    A seed oil that promotes healthy collagen and minimizes the effects of inflammation.

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    Oleic Pau Mulato Extract

    An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.

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    Hyaluronic Acid

    A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in

    Getting started with OS-01 FACE

    Follow these easy steps for optimal results

    • Dispense 1-2 pumps onto fingers
    • Gently massage into skin on the face and neck
    • Use 2 times daily

    All Ingredients

    Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

    Citations

    01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

    02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

    03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims